THE ROLE OF NOTCH PATHWAY IN CARCINOGENESIS
Notch transmembrane receptors family in humans consists of 4 proteins (Notch1–4) which are activated upon direct contact of cells, carrying appropriate ligands of Jagged or Dll families. This interaction leads to certain proteolytic events resulting in Notch intracellular domain translocation to the...
Main Authors: | , , , , |
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Format: | Article |
Language: | Russian |
Published: |
ABV-press
2015-12-01
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Series: | Успехи молекулярной онкологии |
Subjects: | |
Online Access: | https://umo.abvpress.ru/jour/article/view/43 |