THE ROLE OF NOTCH PATHWAY IN CARCINOGENESIS

Notch transmembrane receptors family in humans consists of 4 proteins (Notch1–4) which are activated upon direct contact of cells, carrying appropriate ligands of Jagged or Dll families. This interaction leads to certain proteolytic events resulting in Notch intracellular domain translocation to the...

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Bibliographic Details
Main Authors: M. V. Novikova, V. A. Rybko, N. V. Khromova, M. D. Farmakovskaya, P. B. Kopnin
Format: Article
Language:Russian
Published: ABV-press 2015-12-01
Series:Успехи молекулярной онкологии
Subjects:
Online Access:https://umo.abvpress.ru/jour/article/view/43