THE ROLE OF NOTCH PATHWAY IN CARCINOGENESIS

THE ROLE OF NOTCH PATHWAY IN CARCINOGENESIS

Notch transmembrane receptors family in humans consists of 4 proteins (Notch1–4) which are activated upon direct contact of cells, carrying appropriate ligands of Jagged or Dll families. This interaction leads to certain proteolytic events resulting in Notch intracellular domain translocation to the...

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Библиографические подробности
Главные авторы: M. V. Novikova, V. A. Rybko, N. V. Khromova, M. D. Farmakovskaya, P. B. Kopnin
Формат: Статья
Язык:Russian
Опубликовано: ABV-press 2015-12-01
Серии:Успехи молекулярной онкологии
Предметы:
notch
carcinogenesis
microenvironment
tumor stem cells
epithelia-to-mesenchyma transition
angiogenesis
embryogenesis
signaling pathways
micro-rna
Online-ссылка:https://umo.abvpress.ru/jour/article/view/43

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https://umo.abvpress.ru/jour/article/view/43

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