Micrococcal nuclease sequencing of porcine sperm suggests enriched co-location between retained histones and genomic regions related to semen quality and early embryo development

The mammalian spermatozoon has a unique chromatin structure in which the majority of histones are replaced by protamines during spermatogenesis and a small fraction of nucleosomes are retained at specific locations of the genome. The sperm’s chromatin structure remains unresolved in most animal spec...

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Bibliographic Details
Main Authors: Marta Gòdia, Yu Lian, Marina Naval-Sanchez, Inma Ponte, Joan Enric Rodríguez-Gil, Armand Sanchez, Alex Clop
Format: Article
Language:English
Published: PeerJ Inc. 2023-06-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/15520.pdf