FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy

FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy

Summary: Vasculogenic mimicry (VM) describes the formation of pseudo blood vessels constructed of tumor cells that have acquired endothelial-like properties. VM channels endow the tumor with a tumor-derived vascular system that directly connects to host blood vessels, and their presence is generally...

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Bibliographic Details
Main Authors: Ian G. Cannell, Kirsty Sawicka, Isabella Pearsall, Sophia A. Wild, Lauren Deighton, Sarah M. Pearsall, Giulia Lerda, Fadwa Joud, Showkhin Khan, Alejandra Bruna, Kathryn L. Simpson, Claire M. Mulvey, Fiona Nugent, Fatime Qosaj, Dario Bressan, Caroline Dive, Carlos Caldas, Gregory J. Hannon
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723008021

Internet

http://www.sciencedirect.com/science/article/pii/S2211124723008021

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