Osteopontin is a key player for local adipose tissue macrophage proliferation in obesity

Osteopontin is a key player for local adipose tissue macrophage proliferation in obesity

Objective: Recent findings point towards an important role of local macrophage proliferation also in obesity-induced adipose tissue inflammation that underlies insulin resistance and type 2 diabetes. Osteopontin (OPN) is an inflammatory cytokine highly upregulated in adipose tissue (AT) of obese and...

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Bibliographic Details
Main Authors: Matteo Tardelli, Karina Zeyda, Veronica Moreno-Viedma, Bettina Wanko, Nicole G. Grün, Günther Staffler, Maximilian Zeyda, Thomas M. Stulnig
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816301405

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http://www.sciencedirect.com/science/article/pii/S2212877816301405

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