Different patterns of spreading direction and motor neurons involvement in a cohort of limb‐onset amyotrophic lateral sclerosis patients from Southern Italy: Potential implication on disease course or progression?

Abstract Background Currently, there is a lack of knowledge concerning where the pathological process starts and how the neurodegeneration spreads during the course of amyotrophic lateral sclerosis (ALS). Aims This study aims to evaluate the spreading direction of the disease and the corresponding c...

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Bibliographic Details
Main Authors: Giammarco Milella, Stefano Zoccolella, Daniele Urso, Salvatore Nigro, Ludovica Tamburrino, Valentina Gnoni, Marco Filardi, Giancarlo Logroscino
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Brain and Behavior
Subjects:
Online Access:https://doi.org/10.1002/brb3.2899