Synthesis, spectroscopic characterization and antibacterial screening of novel Mannich bases of Ganciclovir

Biologically active Mannich bases with heteroaromatic ring system of substituted guanine derivative (2-amino-9 [{(1,3 di hydroxy propane-2yl) oxy} methyl] 6-9 dihydro-3H-purine-6-one) (ganciclovir), have been synthesized via Mannich reaction. The aminomethylation of ganciclovir with various biologic...

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Bibliographic Details
Main Authors: Sheela Joshi, Purti Bilgaiyan, Anju Pathak
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535213000452