Neural cell adhesion molecule, NCAM, regulates thalamocortical axon pathfinding and the organization of the cortical somatosensory representation in mouse

To study the potential role of NCAM in the development of thalamocortical (TC) axon topography, wild type and NCAM null mutant mice were analyzed for NCAM expression, projection, and targeting of TC afferents within the somatosensory area of the neocortex. Here we report that NCAM and its α-2,8-link...

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Bibliographic Details
Main Authors: Lilian eEnriquez-Barreto, Cecilia ePalazzetti, Leann H. Brennaman, Patricia F. Maness, Alfonso eFairén
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00076/full