HERVK-mediated regulation of neighboring genes: implications for breast cancer prognosis

HERVK-mediated regulation of neighboring genes: implications for breast cancer prognosis

Abstract Human endogenous retroviruses (HERVs) are the remnants of ancient retroviral infections integrated into the human genome. Although most HERVs are silenced or rendered inactive by various regulatory mechanisms, they retain the potential to influence the nearby genes. We analyzed the regulato...

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Bibliographic Details
Main Authors: Boying Liang, Tengyue Yan, Huilin Wei, Die Zhang, Lanxiang Li, Zengjing Liu, Wen Li, Yuluan Zhang, Nili Jiang, Qiuxia Meng, Guiyang Jiang, Yanling Hu, Jing Leng
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Retrovirology
Subjects:
Human endogenous retrovirus-K
Breast cancer
Neighborhood gene
Immune infiltration
Prognosis
Online Access:https://doi.org/10.1186/s12977-024-00636-z

Internet

https://doi.org/10.1186/s12977-024-00636-z

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