Effect of the 3D Artificial Nichoid on the Morphology and Mechanobiological Response of Mesenchymal Stem Cells Cultured In Vitro

Effect of the 3D Artificial Nichoid on the Morphology and Mechanobiological Response of Mesenchymal Stem Cells Cultured In Vitro

Stem cell fate and behavior are affected by the bidirectional communication of cells and their local microenvironment (the stem cell niche), which includes biochemical cues, as well as physical and mechanical factors. Stem cells are normally cultured in conventional two-dimensional monolayer, with a...

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Bibliographic Details
Main Authors: Andrea Remuzzi, Barbara Bonandrini, Matteo Tironi, Lorena Longaretti, Marina Figliuzzi, Sara Conti, Tommaso Zandrini, Roberto Osellame, Giulio Cerullo, Manuela Teresa Raimondi
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
mesenchymal stem cells
3D culture
artificial niche
mechano-transduction
nuclear pore size
Online Access:https://www.mdpi.com/2073-4409/9/8/1873

Internet

https://www.mdpi.com/2073-4409/9/8/1873

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