TBK1 and IRF3 are potential therapeutic targets in Enterovirus A71-associated diseases.

<h4>Background</h4>Enterovirus A71 (EV-A71) is an important causative agent of hand-foot-and-mouth disease (HFMD) associated with enormous healthcare and socioeconomic burden. Although a range of studies about EV-A71 pathogenesis have been well described, the underlying molecular mechani...

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Bibliographic Details
Main Authors: Wangquan Ji, Tiantian Sun, Dong Li, Shuaiyin Chen, Haiyan Yang, Yuefei Jin, Guangcai Duan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0011001