Inhibitory Effect of Chlorpromazine on RANKL-Induced Osteoclastogenesis in Mouse Bone Marrow Cells
Abstract.: Chlorpromazine (CPZ), the first widely used phenothiazine tranquilizer, is shown to inhibit the action of intracellular calmodulin (CaM) and bone resorption in vivo and in vitro. In this study, CPZ (0.63 – 10 μM) dose-dependently inhibited the formation of tartrate-resistant acid phosphat...
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Makale |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
Elsevier
2011-01-01
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| Seri Bilgileri: | Journal of Pharmacological Sciences |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S1347861319306607 |