Human Amniotic Membrane Mesenchymal Stem Cell-Synthesized PGE<sub>2</sub> Exerts an Immunomodulatory Effect on Neutrophil Extracellular Trap in a PAD-4-Dependent Pathway through EP2 and EP4

Human Amniotic Membrane Mesenchymal Stem Cell-Synthesized PGE<sub>2</sub> Exerts an Immunomodulatory Effect on Neutrophil Extracellular Trap in a PAD-4-Dependent Pathway through EP2 and EP4

Human amniotic membrane mesenchymal stem cells (hAM-MSC) secrete a myriad of components with immunosuppressive activities. In the present research, we aimed to describe the effect of prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) secreted by hAM-MSCs on neutrophil extracellula...

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Bibliographic Details
Main Authors: Gibrán Alejandro Estúa-Acosta, Beatriz Buentello-Volante, Fátima Sofía Magaña-Guerrero, José Eduardo-Aguayo Flores, Oscar Vivanco-Rojas, Ilse Castro-Salas, Karla Zarco-Ávila, Mariana A. García-Mejía, Yonathan Garfias
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
NET
immunomodulation
prostaglandin E<sub>2</sub>
amniotic membrane
mesenchymal stem cells
EP2
Online Access:https://www.mdpi.com/2073-4409/11/18/2831

Internet

https://www.mdpi.com/2073-4409/11/18/2831

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