Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines

Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines

Per- and polyfluoroalkyl substances (PFAS) are ubiquitous environmental contaminants associated with adverse reproductive outcomes including reproductive cancers in women. PFAS can alter normal ovarian function, but the effects of PFAS on ovarian cancer progression and therapy response remain unders...

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Bibliographic Details
Main Authors: Brittany P. Rickard, Xianming Tan, Suzanne E. Fenton, Imran Rizvi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
per- and polyfluoroalkyl substances
PFAS
ovarian cancer
platinum resistance
carboplatin
mitochondrial function
Online Access:https://www.mdpi.com/1422-0067/23/9/5176

Internet

https://www.mdpi.com/1422-0067/23/9/5176

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