Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions

Introduction Randomised controlled trials (RCTs) inform healthcare decisions. It is now apparent that some published RCTs contain false data and some appear to have been entirely fabricated. Systematic reviews are performed to identify and synthesise all RCTs that have been conducted on a given topi...

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Main Authors: Elizabeth Loder, Jill Alison Hayden, David Torgerson, Tianjing Li, Wentao Li, Rui Wang, Ben W Mol, Lisa Bero, Jamie J Kirkham, Lisa Parker, Mike Clarke, Jo C Dumville, Calvin Heal, Lyle Gurrin, Andreas Lundh, Madelon van Wely, Toby Lasserson, Alison Avenell, Neil E O'Connell, Andrew Grey, Jack Wilkinson, George A Antoniou, Kylie Elizabeth Hunter, Patrick Dicker, Zarko Alfirevic, Ella Flemyng, Sarah Lensen, Emma Sydenham, Ginny Barbour, Emily Lam, Gideon Meyerowitz-Katz, James Heathers, Nicholas J L Brown, John Carlisle, Steph Grohmann, Barbara K Redman, Lene Seidler, Kyle A Sheldrick
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/3/e084164.full