VEGF-A-Cleavage by FSAP and Inhibition of Neo-Vascularization

Alternative splicing leads to the secretion of multiple forms of vascular endothelial growth factor-A (VEGF-A) that differ in their activity profiles with respect to neovascularization. FSAP (factor VII activating protease) is the zymogen form of a plasma protease that is activated (FSAPa) upon tiss...

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Bibliographic Details
Main Authors: Özgür Uslu, Joerg Herold, Sandip M. Kanse
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/11/1396