Platelet-rich plasma pretreatment protects anterior cruciate ligament fibroblasts correlated with PI3K-Akt-mTOR pathway under hypoxia condition

Background: /Objective: Biological factors such as platelet-rich plasma (PRP) combined with anterior cruciate ligament (ACL) primary repair technology are used to treat ACL injury. However, the protective mechanism of PRP for ACL fibroblasts under hypoxia condition is still unknown. The aim of this...

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Bibliographic Details
Main Authors: Yanwei Cao, Yue Li, Sai Chuen Fu, Jiewei Shen, Hui Zhang, Chunyan Jiang, Patrick Shu-Hang Yung
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X22000067