CBP/p300 activation promotes axon growth, sprouting, and synaptic plasticity in chronic experimental spinal cord injury with severe disability.

CBP/p300 activation promotes axon growth, sprouting, and synaptic plasticity in chronic experimental spinal cord injury with severe disability.

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The interruption of spinal circuitry following spinal cord injury (SCI) disrupts neural activity and is followed by a failure to mount an effective regenerative response resulting in permanent neurological disability. Functional recovery requires the enhancement of axonal and synaptic plasticity of...

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Bibliographic Details
Main Authors: Franziska Müller, Francesco De Virgiliis, Guiping Kong, Luming Zhou, Elisabeth Serger, Jessica Chadwick, Alexandros Sanchez-Vassopoulos, Akash Kumar Singh, Muthusamy Eswaramoorthy, Tapas K Kundu, Simone Di Giovanni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001310

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https://doi.org/10.1371/journal.pbio.3001310

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