Evolutionary plasticity and functional versatility of CRISPR systems

The principal biological function of bacterial and archaeal CRISPR systems is RNA-guided adaptive immunity against viruses and other mobile genetic elements (MGEs). These systems show remarkable evolutionary plasticity and functional versatility at multiple levels, including both the defense mechani...

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Bibliographic Details
Main Authors: Eugene V. Koonin, Kira S. Makarova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730458/?tool=EBI