Efficient targeting of HIF-1α mediated by YC-1 and PX-12 encapsulated niosomes: potential application in colon cancer therapy

Efficient targeting of HIF-1α mediated by YC-1 and PX-12 encapsulated niosomes: potential application in colon cancer therapy

Abstract A number of molecular biofactors have been documented in pathogenesis and poor prognosis of colorectal cancer (CRC). Among them, the Hypoxia-Inducible Factor (HIF-1a) is frequently reported to become over-expressed, and its targeting could restrict and control a variety of essential hallmar...

Full description

Bibliographic Details
Main Authors: Azar Bakand, Sevil Vaghefi Moghaddam, Maryam Naseroleslami, Helder André, Neda Mousavi-Niri, Effat Alizadeh
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Biological Engineering
Subjects:
Colon cancer
Drug delivery
Niosome
HIF-1α
YC-1
PX-12
Online Access:https://doi.org/10.1186/s13036-023-00375-3

Internet

https://doi.org/10.1186/s13036-023-00375-3

Similar Items