PILRA polymorphism modifies the effect of APOE4 and GM17 on Alzheimer’s disease risk

PILRA polymorphism modifies the effect of APOE4 and GM17 on Alzheimer’s disease risk

Abstract PILRA (rs1859788 A > G) has been suggested to be a protective variant for Alzheimer’s disease (AD) and is an entry co-receptor for herpes simplex virus-1. We conducted a nested case–control study of 360 1:1-matched AD subjects. Interactions between the PILRA-A allele, APOE risk variants...

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Bibliographic Details
Main Authors: Karin Lopatko Lindman, Caroline Jonsson, Bodil Weidung, Jan Olsson, Janardan P. Pandey, Dmitry Prokopenko, Rudolph E. Tanzi, Göran Hallmans, Sture Eriksson, Fredrik Elgh, Hugo Lövheim
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-17058-6

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https://doi.org/10.1038/s41598-022-17058-6

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