Ca<sup>2+</sup> Sensors Assemble: Function of the MCU Complex in the Pancreatic Beta Cell

The Mitochondrial Calcium Uniporter Complex (MCU Complex) is essential for β-cell function due to its role in sustaining insulin secretion. The MCU complex regulates mitochondrial Ca<sup>2+</sup> influx, which is necessary for increased ATP production following cellular glucose uptake, k...

Full description

Bibliographic Details
Main Authors: Jack G. Allen, Jeffery S. Tessem
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/13/1993