Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes

Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes

Abstract Macromolecular protein complexes carry out many of the essential functions of cells, and many genetic diseases arise from disrupting the functions of such complexes. Currently, there is great interest in defining the complete set of human protein complexes, but recent published maps lack co...

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Bibliographic Details
Main Authors: Kevin Drew, Chanjae Lee, Ryan L Huizar, Fan Tu, Blake Borgeson, Claire D McWhite, Yun Ma, John B Wallingford, Edward M Marcotte
Format: Article
Language:English
Published: Springer Nature 2017-06-01
Series:Molecular Systems Biology
Subjects:
cilia
ciliopathy
human interactome
mass spectrometry
protein complexes
proteomics
Online Access:https://doi.org/10.15252/msb.20167490

Internet

https://doi.org/10.15252/msb.20167490

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