Topical Application of KAJD Attenuates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis Symptoms Through Regulation of IgE and MAPK Pathways in BALB/C Mice and Several Immune Cell Types

Topical Application of KAJD Attenuates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis Symptoms Through Regulation of IgE and MAPK Pathways in BALB/C Mice and Several Immune Cell Types

Atopic dermatitis (AD) is a frequent skin complication that is caused by unknown reasons. KHU-ATO-JIN-D (KAJD) is a new drug aimed at AD composed of a mixture of extracts from six plants known to have anti-inflammatory and antiallergic effects. This study investigated whether KAJD alleviates 2,4-din...

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Bibliographic Details
Main Authors: Se Hyang Hong, Jin Mo Ku, Hyo In Kim, Tai Young Kim, Hye Sook Seo, Yong Cheol Shin, Seong-Gyu Ko
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
atopic dermatitis
mast cell
splenocyte
macrophage
IgE
CD4+ T cells
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01097/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01097/full

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