Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8

Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8

Summary: Phosphate (Pi) serves countless metabolic pathways and is involved in macromolecule synthesis, energy storage, cellular signaling, and bone maintenance. Herein, we describe the coordination of Pi uptake and efflux pathways to maintain mammalian cell Pi homeostasis. We discover that XPR1, th...

Full description

Bibliographic Details
Main Authors: Xingyao Li, Regan B. Kirkpatrick, Xiaodong Wang, Charles J. Tucker, Anuj Shukla, Henning J. Jessen, Huanchen Wang, Stephen B. Shears, Chunfang Gu
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724006442

Internet

http://www.sciencedirect.com/science/article/pii/S2211124724006442

Similar Items