Cellular heterogeneity in the 16HBE14o− airway epithelial line impacts biological readouts

Abstract The airway epithelial cell line, 16HBE14o−, is an important cell model for studying airway disease. 16HBE14o− cells were originally generated from primary human bronchial epithelial cells by SV40‐mediated immortalization, a process that is associated with genomic instability through long‐te...

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Bibliographic Details
Main Authors: Jenny L. Kerschner, Alekh Paranjapye, Ann Harris
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15700