Non-H3 CDR template selection in antibody modeling through machine learning

Antibodies are proteins generated by the adaptive immune system to recognize and counteract a plethora of pathogens through specific binding. This adaptive binding is mediated by structural diversity in the six complementary determining region (CDR) loops (H1, H2, H3, L1, L2 and L3), which also make...

Descrición completa

Detalles Bibliográficos
Main Authors: Xiyao Long, Jeliazko R. Jeliazkov, Jeffrey J. Gray
Formato: Artigo
Idioma:English
Publicado: PeerJ Inc. 2019-01-01
Series:PeerJ
Subjects:
Acceso en liña:https://peerj.com/articles/6179.pdf