Association between altered metabolism and genetic mutations in human glioma
Abstract Background Molecular markers for classification of gliomas include isocitrate dehydrogenase (IDH) mutations and codeletion of chromosomal arms 1p and 19q (1p/19q). While mutations in IDH enzymes result in the well‐characterized production of oncometabolite 2‐hydroxyglutarate, dysregulation...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-05-01
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Series: | Cancer Reports |
Subjects: | |
Online Access: | https://doi.org/10.1002/cnr2.1799 |