Hypoxia-inducible factor expression is related to apoptosis and cartilage degradation in temporomandibular joint osteoarthritis

Abstract Background It remains unclear etiology of cartilaginous tissues in osteoarthritis (OA) lesions. In this study, we hypothesized the accumulation of hypoxia-inducible factor (HIF) and activated apoptosis relate to condylar cartilage degeneration in vivo. Methods Malocclusion stress was applie...

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Bibliographic Details
Main Authors: Jun Zhang, Yu Hu, Zihan Wang, Xuelian Wu, Chun Yang, Hefeng Yang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12891-022-05544-x