A fifty-year odyssey: prospects for a cytomegalovirus vaccine in transplant and congenital infection

A fifty-year odyssey: prospects for a cytomegalovirus vaccine in transplant and congenital infection

Introduction: It has been almost fifty years since the Towne strain was used by Plotkin and collaborators as the first vaccine candidate for cytomegalovirus (CMV). While that approach showed partial efficacy, there have been a multitude of challenges to improve on the promise of a CMV vaccine. Effor...

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Bibliographic Details
Main Authors: Don Jeffrey Diamond, Corinna La Rosa, Flavia Chiuppesi, Heidi Contreras, Sanjeet Dadwal, Felix Wussow, Supriya Bautista, Ryotaro Nakamura, John A. Zaia
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Expert Review of Vaccines
Subjects:
antivirals
cytomegalovirus
ganciclovir
immune response
letermovir
solid organ transplant
congenital infection
stem cell transplant
subunit vaccine
viral vector
Online Access:http://dx.doi.org/10.1080/14760584.2018.1526085

Internet

http://dx.doi.org/10.1080/14760584.2018.1526085

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