Effect of Puumala hantavirus infection on Human Umbilical Vein Endothelial Cell hemostatic function: platelet interactions, increased tissue factor expression and fibrinolysis regulator release

Effect of Puumala hantavirus infection on Human Umbilical Vein Endothelial Cell hemostatic function: platelet interactions, increased tissue factor expression and fibrinolysis regulator release

Puumala virus (PUUV) infection causes over 5000 cases of hemorrhagic fever in Europe annually and can influence the hemostatic balance extensively. Infection might lead to hemorrhage, while a recent study showed an increased risk of myocardial infarction during or shortly after PUUV infection. The m...

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Bibliographic Details
Main Authors: Marco Goeijenbier, Joost CM Meijers, Fatih Anfasa, Jeroen Roose, Cornelia AM Van de Weg, Kamran Bakhtiari, Heikki Henttonen, Antti Vaheri, Albert Osterhaus, Eric C.M. Van Gorp, Byron Emanuel Eusebio Martina
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Microbiology
Subjects:
Endothelial Cells
Hantavirus
Hemorrhagic Fever with Renal Syndrome
Hemorrhagic Fevers, Viral
Hemostasis
platelets
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00220/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00220/full

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