5-Methylcytosine and 5-Hydroxymethylcytosine Signatures Underlying Pediatric Cancers

In addition to the genetic variations, recent evidence has shown that DNA methylation of both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) underlies the pathogenesis of pediatric cancer. Given the high mortality rate, there is an urgent need to study the mechanisms contributing to the p...

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Bibliographic Details
Main Authors: Shalu Jhanwar, Ajinkya Deogade
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Epigenomes
Subjects:
Online Access:https://www.mdpi.com/2075-4655/3/2/9