Dissociable effects of oxycodone on behavior, calcium transient activity, and excitability of dorsolateral striatal neurons

Opioids are the most common medications for moderate to severe pain. Unfortunately, they also have addictive properties that have precipitated opioid misuse and the opioid epidemic. In the present study, we examined the effects of acute administration of oxycodone, a μ-opioid receptor (MOR) agonist,...

Full description

Bibliographic Details
Main Authors: Joshua Barry, Katerina D. Oikonomou, Allison Peng, Daniel Yu, Chenyi Yang, Peyman Golshani, Christopher J. Evans, Michael S. Levine, Carlos Cepeda
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncir.2022.983323/full