Nivolumab Induced Thyroid Dysfunction: Unusual Clinical Presentation and Challenging Diagnosis

Nivolumab Induced Thyroid Dysfunction: Unusual Clinical Presentation and Challenging Diagnosis

In recent years, immune checkpoint inhibitors (ICIs) had a great impact in cancer therapy. ICIs display a peculiar toxicity profile, which is characterized by autoimmune-like manifestations against multiple organs, including endocrine glands. We hereby report the case history of two patients who exp...

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Bibliographic Details
Main Authors: Carmine Iadarola, Laura Croce, Erica Quaquarini, Cristina Teragni, Sara Pinto, Antonio Bernardo, Rodolfo Fonte, Michele Marinò, Mario Rotondi, Luca Chiovato
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Endocrinology
Subjects:
thyroid
graves' disease
nivolumab
immune checkpoint inhibitors
PD-1
autoimmune
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00813/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00813/full

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