Biomarker Discordances and Alterations Observed in Breast Cancer Treated with Neoadjuvant Chemotherapy: Causes, Frequencies, and Clinical Significances

Biomarker Discordances and Alterations Observed in Breast Cancer Treated with Neoadjuvant Chemotherapy: Causes, Frequencies, and Clinical Significances

Purpose: Biomarker discordances and alterations can be encountered between tru-cut biopsy and residual tumor in breast cancer treated with neoadjuvant chemotherapy (NACTx). We aimed to investigate the effect of NACTx on major biomarker expression (ER, PR, HER2, Ki-67) and tumor grade, the frequency...

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Bibliographic Details
Main Authors: Cengiz Yilmaz, Demet Kocatepe Cavdar
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Current Oncology
Subjects:
breast cancer
neoadjuvant chemotherapy
biomarker discordance
biomarker alteration
chemosensitivity
Online Access:https://www.mdpi.com/1718-7729/29/12/761

Internet

https://www.mdpi.com/1718-7729/29/12/761

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