CWC22 Connects Pre-mRNA Splicing and Exon Junction Complex Assembly
The exon junction complex (EJC) is a key regulator of posttranscriptional mRNA fate and binds to mRNA during splicing. Although the composition of EJCs is well understood, the mechanism mediating splicing-dependent EJC assembly and the factor(s) recruiting the EJC remain elusive. Here, we identify C...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-09-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124712002574 |