CWC22 Connects Pre-mRNA Splicing and Exon Junction Complex Assembly

CWC22 Connects Pre-mRNA Splicing and Exon Junction Complex Assembly

The exon junction complex (EJC) is a key regulator of posttranscriptional mRNA fate and binds to mRNA during splicing. Although the composition of EJCs is well understood, the mechanism mediating splicing-dependent EJC assembly and the factor(s) recruiting the EJC remain elusive. Here, we identify C...

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Bibliographic Details
Main Authors: Anna-Lena Steckelberg, Volker Boehm, Agnieszka M. Gromadzka, Niels H. Gehring
Format: Article
Language:English
Published: Elsevier 2012-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712002574

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