Effects of Icariin and Its Metabolites on GPCR Regulation and MK-801-Induced Schizophrenia-Like Behaviors in Mice

Effects of Icariin and Its Metabolites on GPCR Regulation and MK-801-Induced Schizophrenia-Like Behaviors in Mice

Icariin, a major bioactive compound found in the <i>Epimedium</i> genus, has been reported to exert protective effects against neurodegenerative disorders. In the current study, we aimed to investigate the regulatory effect of icariin and its active metabolites (icariside II and icaritin...

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Bibliographic Details
Main Authors: Su Hui Seong, Seo Hyun Kim, Jong Hoon Ryu, Jin-Woo Jeong, Hyun Ah Jung, Jae Sue Choi
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Molecules
Subjects:
icariin
icariside II
GPCR
schizophrenia
MK-801
Online Access:https://www.mdpi.com/1420-3049/28/21/7300

Internet

https://www.mdpi.com/1420-3049/28/21/7300

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