Computation of Antigenicity Predicts SARS-CoV-2 Vaccine Breakthrough Variants

Computation of Antigenicity Predicts SARS-CoV-2 Vaccine Breakthrough Variants

It has been reported that multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) including Alpha, Beta, Gamma, and Delta can reduce neutralization by antibodies, resulting in vaccine breakthrough infections. Virus–antiserum neutralization assays are typicall...

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Bibliographic Details
Main Authors: Ye-Fan Hu, Jing-Chu Hu, Hua-Rui Gong, Antoine Danchin, Ren Sun, Hin Chu, Ivan Fan-Ngai Hung, Kwok Yung Yuen, Kelvin Kai-Wang To, Bao-Zhong Zhang, Thomas Yau, Jian-Dong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
variants of concern
antigenicity prediction
vaccine breakthrough variants
computation of antigenicity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.861050/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.861050/full

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