Response Type and Host Species may be Sufficient to Predict Dose-Response Curve Shape for Adenoviral Vector Vaccines

Vaccine dose-response curves can follow both saturating and peaking shapes. Dose-response curves for adenoviral vector vaccines have not been systematically described. In this paper, we explore the dose-response shape of published adenoviral animal and human studies. Where data were informative, dos...

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Bibliographic Details
Main Authors: John Benest, Sophie Rhodes, Sara Afrough, Thomas Evans, Richard White
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/2/155