Germ-line mutations in epidermal growth factor receptor (<it>EGFR) </it>are rare but may contribute to oncogenesis: A novel germ-line mutation in <it>EGFR </it>detected in a patient with lung adenocarcinoma

Germ-line mutations in epidermal growth factor receptor (<it>EGFR) </it>are rare but may contribute to oncogenesis: A novel germ-line mutation in <it>EGFR </it>detected in a patient with lung adenocarcinoma

<p>Abstract</p> <p>Background</p> <p>A subset of lung cancer patients harbour <it>EGFR </it>somatic mutations in their tumours and are candidates for treatment with EGFR tyrosine kinase inhibitors. In a few cases <it>EGFR </it>mutations have also...

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Bibliographic Details
Main Authors: Menéndez Primitiva, Iglesias Fernando, González-Arriaga Patricia, Osorio Fernando G, Pitiot Ana S, Astudillo Aurora, Santamaría Iñigo, Blay Pilar, Centeno Irene, Tardón Adonina, Freije Jose M, Balbín Milagros
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/172

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http://www.biomedcentral.com/1471-2407/11/172

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