Methods for Collection of Extracellular Vesicles and Their Content RNA as Liquid Biopsy for Lung Cancer Detection: Application of Differential Centrifugation and Annexin A5 Coated Beads

Methods for Collection of Extracellular Vesicles and Their Content RNA as Liquid Biopsy for Lung Cancer Detection: Application of Differential Centrifugation and Annexin A5 Coated Beads

Extracellular vesicles (EVs) contain abundant extracellular RNA (exRNA), which can be a valuable source of liquid biopsy. However, as various RNA species exist in different types of EVs, lack of detailed characterization of these RNA species and efficient collection methods limits the clinical appli...

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Bibliographic Details
Main Authors: Mei-Chia Wang, Guan-Yu Gong, Chih-Liang Wang, How-Wen Ko, Rong-Xuan Weng, Pi-Yueh Chang, Chiuan-Chian Chiou
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Current Issues in Molecular Biology
Subjects:
extracellular vesicles
annexin A5 beads
extracellular RNA
liquid biopsy
non-small-cell lung cancer
Online Access:https://www.mdpi.com/1467-3045/44/5/162

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https://www.mdpi.com/1467-3045/44/5/162

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