To investigate the tumor promotion role of PLOD3 in colorectal cancer and its potential as a prognostic biomarker and therapeutic target

To investigate the tumor promotion role of PLOD3 in colorectal cancer and its potential as a prognostic biomarker and therapeutic target

Abstract PLOD3 (procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3), a key enzyme involved in collagen post-translational modification, is critical for maintaining the structural integrity of the extracellular matrix (ECM). Dysregulation of PLOD3 has been implicated in various malignancies, includin...

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Bibliographic Details
Main Authors: Wanhui Dong, Su Li, Wei Tang, Qingming Sun, Pei Zhu, Mingxing Wang, Bin Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
CRC
Colorectal cancer
Mendelian
PLOD3
PLOD family
Online Access:https://doi.org/10.1038/s41598-025-89521-z

Internet

https://doi.org/10.1038/s41598-025-89521-z

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