Ponatinib Protects Mice From Lethal Influenza Infection by Suppressing Cytokine Storm

Ponatinib Protects Mice From Lethal Influenza Infection by Suppressing Cytokine Storm

Excessive inflammation associated with the uncontrolled release of pro-inflammatory cytokines is the main cause of death from influenza virus infection. Previous studies have indicated that inhibition of interferon gamma-induced protein 10 (IP-10), interleukin-8 (IL-8), monocyte chemoattractant prot...

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Bibliographic Details
Main Authors: Si Chen, Ge Liu, Jungang Chen, Ao Hu, Li Zhang, Wenyu Sun, Wei Tang, Chunlan Liu, Haiwei Zhang, Chang Ke, Jianguo Wu, Xulin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
cytokine storm
immunomodulator
influenza A virus
ponatinib
pro-inflammatory cytokine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01393/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01393/full

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