Interplay of channels, pumps and organelle location in calcium microdomain formation
To analyze the influence of Ca ^2+ microdomains on the global cytosolic Ca ^2+ concentration, we consider the polarization and activation of T-cells after the formation of an immunological synapse as a model system. For T-cell proliferation and activation, a high and robust Ca ^2+ signal lasting fro...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IOP Publishing
2013-01-01
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| Series: | New Journal of Physics |
| Online Access: | https://doi.org/10.1088/1367-2630/15/5/055022 |