The Radiolabeling of a Gly-Sar Dipeptide Derivative with Flourine-18 and Its Use as a Potential Peptide Transporter PET Imaging Agent

We have developed a novel fluorine-18 radiotracer, dipeptide <b>1</b>, radiolabeled in two steps from mesylate <b>3</b>. The initial radiolabeling is achieved in a short reaction time (10 min) and purified through solid-phase extraction (SPE) with modest radiochemical yields...

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Bibliographic Details
Main Authors: Andrei Molotkov, John W. Castrillon, Sreevidya Santha, Paul E. Harris, David K. Leung, Akiva Mintz, Patrick Carberry
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/3/643