Tailoring the antibody response to aggregated Aß using novel Alzheimer-vaccines.

Tailoring the antibody response to aggregated Aß using novel Alzheimer-vaccines.

Recent evidence suggests Alzheimer-Disease (AD) to be driven by aggregated Aß. Capitalizing on the mechanism of molecular mimicry and applying several selection layers, we screened peptide libraries for moieties inducing antibodies selectively reacting with Aß-aggregates. The technology identified a...

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Bibliographic Details
Main Authors: Markus Mandler, Radmila Santic, Petra Gruber, Yeliz Cinar, Dagmar Pichler, Susanne Aileen Funke, Dieter Willbold, Achim Schneeberger, Walter Schmidt, Frank Mattner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0115237

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https://doi.org/10.1371/journal.pone.0115237

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