Role of Akt Activation in PARP Inhibitor Resistance in Cancer
Poly(ADP-ribose) polymerase (PARP) inhibitors have recently been introduced in the therapy of several types of cancers not responding to conventional treatments. However, <i>de novo</i> and acquired PARP inhibitor resistance is a significant limiting factor in the clinical therapy, and t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-02-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/12/3/532 |