Broad HIV epitope specificity and viral inhibition induced by multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults.

Broad HIV epitope specificity and viral inhibition induced by multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults.

A correlation between in vivo and in vitro virus control mediated by CD8+ T-cell populations has been demonstrated by CD8 T-cell-mediated inhibition of HIV-1 and SIV replication in vitro in peripheral blood mononuclear cells (PBMCs) from infected humans and non-human primates (NHPs), respectively. H...

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Bibliographic Details
Main Authors: Jakub Kopycinski, Peter Hayes, Ambreen Ashraf, Hannah Cheeseman, Francesco Lala, Justyna Czyzewska-Khan, Aggeliki Spentzou, Dilbinder K Gill, Michael C Keefer, Jean-Louis Excler, Patricia Fast, Josephine Cox, Jill Gilmour
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946500?pdf=render

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http://europepmc.org/articles/PMC3946500?pdf=render

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