Tributyrin, a Butyrate Pro-Drug, Primes Satellite Cells for Differentiation by Altering the Epigenetic Landscape

Tributyrin, a Butyrate Pro-Drug, Primes Satellite Cells for Differentiation by Altering the Epigenetic Landscape

Satellite cells (SC) are a population of muscle resident stem cells that are responsible for postnatal muscle growth and repair. With investigation into the genomic regulation of SC fate, the role of the epigenome in governing SC myogenesis is becoming clearer. Histone deacetylase (HDAC) inhibitors...

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Bibliographic Details
Main Authors: Robert L. Murray, Wei Zhang, Jianan Liu, Jason Cooper, Alex Mitchell, Maria Buman, Jiuzhou Song, Chad H. Stahl
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
satellite cell
butyrate
epigenetics
ChIP-Seq
myogenic differentiation
HDAC inhibitor
Online Access:https://www.mdpi.com/2073-4409/10/12/3475

Internet

https://www.mdpi.com/2073-4409/10/12/3475

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