STX2 Promotes Trophoblast Growth, Migration, and Invasion Through Activation of the PI3K-AKT Pathway in Preeclampsia

STX2 Promotes Trophoblast Growth, Migration, and Invasion Through Activation of the PI3K-AKT Pathway in Preeclampsia

ObjectivesAbnormal trophoblast behaviors during pregnancy contribute to the development of preeclampsia (PE). Syntaxin2 (STX2) has been shown to be a crucial epithelial mediator in numerous diseases. However, the functions of STX2 and the mechanisms underlying its role in PE remain largely unknown....

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Bibliographic Details
Main Authors: Yan Li, Xian-li Sun, Chun-ling Ma, Chao Li, Ying Zhan, Wen-ting Li, Can Li, Yi-hao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
syntaxin2
trophoblast
PI3K
AKT
preeclampsia
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.615973/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.615973/full

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